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  • Title: Macroscopic Sertoli cell nodule of the testis containing numerous spermatogonia.
    Author: Roth LM, Czernobilsky B.
    Journal: Pathol Res Pract; 2016 Oct; 212(10):943-945. PubMed ID: 27473668.
    Abstract:
    Sertoli cell nodule consists of clusters of seminiferous tubules composed of immature Sertoli cells and, in some cases, spermatogonia. We report a case of macroscopic Sertoli cell nodule that occurred in the descended left testis of a 26-year-old man. The nodule was centrally located and measured 1.7cm in greatest dimension, the largest such lesion reported to date. Spermatogonia were prominent, a feature that is particularly common in the larger nodules. Macroscopic Sertoli cell nodules (greater than 0.5cm) typically occur in a descended testis. The age range of patients in cases reported since the year 2000 is 19-36 years. Unlike incidental Sertoli cell nodules, macroscopic Sertoli cell nodules containing numerous germ cells can be mistaken for several other Sertoli cell and germ cell lesions and neoplasms.
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