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  • Title: [Cytodiagnosis by fine-needle aspiration (FNAB) in thyroid dysplasias and neoplasms observed in 1983-1987].
    Author: Gabrielli M, Gaetti L, Melissari M.
    Journal: Minerva Med; 1989 May; 80(5):435-8. PubMed ID: 2747970.
    Abstract:
    Cytology using fine needle aspiration biopsy has been widely used in dysplastic and neoplastic thyroid lesions as it is free of complications and very accurate. Personal experience with 2212 thyroid fine needle aspiration biopsies (1564 patients) performed in the period 1983-1987 is reported. Cytologic and histologic diagnoses are compared with respect to 139 patients. Diagnostic accuracy was 85.61%, with 9 false negatives (6.45%) and 11 false positives (7.51%). Sensitivity was higher in papillary thyroid carcinomas and Hürthle cell neoplasias than in follicular neoplasias and nodular goitres (89.66% and 90% versus 79.47% and 87.03% respectively). The false positives observed in follicular neoplasias depend on the limitations of cytologic and histologic analyses. Fine needle aspiration biopsy makes it possible to select candidates for thyroidectomy although in some cases surgical exploration is required for diagnosis.
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