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  • Title: Contact Lens-induced Limbal Stem Cell Deficiency.
    Author: Rossen J, Amram A, Milani B, Park D, Harthan J, Joslin C, McMahon T, Djalilian A.
    Journal: Ocul Surf; 2016 Oct; 14(4):419-434. PubMed ID: 27480488.
    Abstract:
    Limbal stem cell deficiency (LSCD) is a pathologic condition caused by the dysfunction and/or destruction of stem cell precursors of the corneal epithelium, typified clinically by corneal conjunctivalization. The purpose of this review is to critically discuss a less well-known cause of limbal stem cell disease: contact lens (CL) wear. A literature search was conducted to include original articles containing patients with CL-induced LSCD. This review describes epidemiology, diagnostic strategies, pathogenesis, differential diagnosis, and treatment modalities for this condition.
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