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  • Title: Klippel-Trénaunay Syndrome: Need for Careful Clinical Classification.
    Author: Volz KR, Kanner CD, Evans J, Evans KD.
    Journal: J Ultrasound Med; 2016 Sep; 35(9):2057-65. PubMed ID: 27492391.
    Abstract:
    Klippel-Trénaunay syndrome (KTS) is a rare congenital malformation characterized by a triad of clinical presentations: (1) capillary malformations manifesting as a "port wine stain"; (2) limb hypertrophy; and (3) venous varicosities. It is distinguished from Parkes-Weber syndrome by the absence of substantial arteriovenous shunting. Due to the clinical implications of an arteriovenous fistula, differentiation between the two syndromes is important, as the prognosis and treatment greatly differ. We present a series of 5 cases of suspected KTS, while emphasizing the difficulties in distinguishing KTS from Parkes-Weber syndrome without diagnostic imaging and underscoring the importance of accurately classifying patients with the appropriate syndrome.
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