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  • Title: Severe chronic osteomyelitis caused by Morganella morganii with high population diversity.
    Author: Zhu J, Li H, Feng L, Yang M, Yang R, Yang L, Li L, Li R, Liu M, Hou S, Ke Y, Li W, Bai F.
    Journal: Int J Infect Dis; 2016 Sep; 50():44-7. PubMed ID: 27495005.
    Abstract:
    A case of chronic osteomyelitis probably caused by Morganella morganii, occurring over a period of 30 years, is reported. The organism was identified through a combination of sample culture, direct sequencing, and 16S RNA gene amplicon sequencing. Further whole-genome sequencing and population structure analysis of the isolates from the patient showed the bacterial population to be highly diverse. This case provides a valuable example of a long-term infection caused by an opportunistic pathogen, M. morganii, with high diversity, which might evolve during replication within the host.
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