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  • Title: Serratia marcescens outbreak due to contaminated 2% aqueous chlorhexidine.
    Author: de Frutos M, López-Urrutia L, Domínguez-Gil M, Arias M, Muñoz-Bellido JL, Eiros JM, Ramos C.
    Journal: Enferm Infecc Microbiol Clin; 2017 Dec; 35(10):624-629. PubMed ID: 27495382.
    Abstract:
    INTRODUCTION AND OBJECTIVE: An outbreak of Serratia marcescens infections outbreak is described, as well as the epidemiological study that linked the outbreak to the use of 2% aqueous chlorhexidine antiseptic. METHOD: In late November 2014 an increasing incidence of S. marcescens isolates was detected in patients treated in the emergency department. It was considered a possible outbreak, and an epidemiological investigation was started. RESULT: S. marcescens was isolated in 23 samples from 16 patients and in all new bottles of two lots of 2% aqueous chlorhexidine. The contaminated disinfectant was withdrawn, and the Spanish Drugs Agency was alerted (COS 2/2014). The epidemiological study showed that strains isolated from clinical samples and from chlorhexidine belonged to the same clone. No further isolates were obtained once the disinfectant was withdrawn. CONCLUSION: The suspicion of an outbreak and the epidemiological study were essential to control the incidence.
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