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  • Title: Isolated ileal ganglioneuromatosis in an 11-year-old boy: Case report and review of literature.
    Author: Mitra S, Mukherjee S, Chakraborty H.
    Journal: Indian J Pathol Microbiol; 2016; 59(3):365-7. PubMed ID: 27510679.
    Abstract:
    Ganglioneuromatous proliferation in the gastrointestinal tract is a rare occurrence and is usually associated with specific syndrome complexes such as multiple endocrine neoplasia Type 2B or von Recklinghausen's disease. We report here a case of diffuse intestinal ganglioneuromatosis, presenting as intestinal obstruction and chronic constipation in an 11-year-old boy. Sporadic cases of intestinal ganglioneuromatosis in the absence of any systemic manifestations are a very rare cause of enteric motility disorders in childhood, and we discuss the pathological and clinical significance of this finding. Histopathological identification of this uncommon cause of a common pediatric problem is important since the condition is amenable to surgical treatment.
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