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  • Title: Cyclen lanthanide-based micellar structures for application as luminescent [Eu(iii)] and magnetic [Gd(iii)] resonance imaging (MRI) contrast agents.
    Author: Surender EM, Comby S, Martyn S, Cavanagh B, Lee TC, Brougham DF, Gunnlaugsson T.
    Journal: Chem Commun (Camb); 2016 Sep 18; 52(72):10858-61. PubMed ID: 27523566.
    Abstract:
    The synthesis of coordinatively unsaturated tetra-substituted 1,4,7,10-tetraazacyclododecane (cyclen) lanthanide complexes is described; these structures, possessing hydrophobic (C12-alkyl) tails and hydrophilic head groups, self-assemble into supramolecular micellar structures in aqueous solution, and hence can be utilised as novel contrast agents for MRI.
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