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  • Title: Gd-DTPA enhanced high resolution MR imaging of pituitary adenomas.
    Author: Steiner E, Imhof H, Knosp E.
    Journal: Radiographics; 1989 Jul; 9(4):587-98. PubMed ID: 2756189.
    Abstract:
    Thirty-eight patients with surgically or biochemically confirmed pituitary adenomas were examined on a 1.5 T MRI system by means of spin echo technique with 3 mm slice thickness. T1 weighted sagittal and coronal sections were obtained before and after the administration of Gd-DTPA. Compared with the normal pituitary anterior lobe, 8% of the adenomas were hyperintense, 45% were isointense, 42% were hypointense and 5% were inhomogeneously intense. After Gd-DTPA administration, 13% enhanced to a greater degree, 10% to the same, and 57% to a lesser degree than the normal pituitary tissue. Twenty percent showed inhomogeneous enhancement. In 10%, there was evidence of adenoma only in the enhanced images. The delineation of the adenoma from the cavernous sinus was improved from 47% in unenhanced scans to 91% after Gd-DTPA administration.
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