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  • Title: Vaccine-induced rabies case in a cow (Bos taurus): Molecular characterisation of vaccine strain in brain tissue.
    Author: Vuta V, Picard-Meyer E, Robardet E, Barboi G, Motiu R, Barbuceanu F, Vlagioiu C, Cliquet F.
    Journal: Vaccine; 2016 Sep 22; 34(41):5021-5025. PubMed ID: 27576075.
    Abstract:
    Rabies is a fatal neuropathogenic zoonosis caused by the rabies virus of the Lyssavirus genus, Rhabdoviridae family. The oral vaccination of foxes - the main reservoir of rabies in Europe - using a live attenuated rabies virus vaccine was successfully conducted in many Western European countries. In July 2015, a rabies vaccine strain was isolated from the brain tissues of a clinically suspect cow (Bos taurus) in Romania. The nucleotide analysis of both N and G gene sequences showed 100% identity between the rabid animal, the GenBank reference SAD B19 strain and five rabies vaccine batches used for the national oral vaccination campaign targeting foxes.
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