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  • Title: [Human herpes virus 6 infection in an inmunocompetent patient with carbamazepine-induced DRESS syndrome].
    Author: Álvarez S, Delama I, Navajas-Galimany L, Eymin G, Ceballos ME, Andino-Navarrete R.
    Journal: Rev Chilena Infectol; 2016 Jun; 33(3):340-5. PubMed ID: 27598287.
    Abstract:
    DRESS syndrome (drug reaction with eosinophilia and systemic symptoms) is an adverse life-threatening drug reaction characterized by a polymorphous rash associated with fever, lymphadenopathy and multiorgan involvement with eosinophilia. We present the case of an immunocompetent man with DRESS syndrome secondary to carbamazepine, that developed concomitantly meningoencephalitis caused by human herpes virus 6 (HHV-6), and a review of literature. The pathogenic role of HHV-6 in DRESS syndrome remains controversial. Given the diagnostic and possibly prognostic significance of HHV-6, the screening seems to be a good measure to use in the clinical management of these patients.
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