These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Determination of flonicamid and its metabolites in bell pepper using ultra-high-performance liquid chromatography coupled to high-resolution mass spectrometry (Orbitrap).
    Author: López-Ruiz R, Romero-González R, Martínez Vidal JL, Garrido Frenich A.
    Journal: Food Addit Contam Part A Chem Anal Control Expo Risk Assess; 2016 Nov; 33(11):1685-1692. PubMed ID: 27598508.
    Abstract:
    The development and validation of a method to determine flonicamid and its metabolites as TFNA (4-trifluoromethylnicotinic acid), TFNG (N-(4-trifluoromethylnicotinoyl) glycine) and TFNA-AM (4-trifluoromethylnicotinamide) in bell pepper samples by ultra-high-performance liquid chromatography coupled to Orbitrap mass spectrometry (UHPLC-Orbitrap-MS) was performed. A fast and simple extraction procedure with acidified acetonitrile and salts (magnesium sulfate and sodium chloride) was used. The methodology was validated, checking for specificity, recovery, precision, limits of detection (LODs) and limits of quantification (LOQs). The recoveries ranged from 84% to 98%, and precisions were lower than 17%. Finally, LODs ranged from 1 µg kg-1 (flonicamid) to 6 µg kg-1 (TFNA-AM), while LOQs ranged from 10 µg kg-1 (flonicamid) to 30 µg kg-1 (TFNA-AM). Bell pepper samples were analysed and concentrations up to 98 µg kg-1 (flonicamid) were detected, although the sum of flonicamid and metabolites did not exceed the maximum residue limit (MRL) set by the European Union.
    [Abstract] [Full Text] [Related] [New Search]