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  • Title: [Clinical and immunologic aspects of chlamydial infections in infertile women].
    Author: Jevremović M, Vidaković B, Krstić L, Zizić V, Kovacević D, Pazin S, Milenković V, Velimirović M.
    Journal: Med Pregl; 1989; 42(1-2):25-8. PubMed ID: 2761474.
    Abstract:
    UNLABELLED: Chlamydia Trachomatis (CT) infection of the genital tract ranges from clinically severe to the silent subclinical forms of pelvic inflammatory diseases which can result in fallopian tubes obstruction and subsequent infertility. Our investigations: The serum antichlamydial antibodies of 30 infertile patients and the cultures of Chlamydia Trachomatis from specimens of endometrial biopsies were determined as well as HSG and laparoscopic examinations. METHODOLOGY: The evaluation of serum antichlamydial antibodies were measured by ELISA test. The endometrial specimens for culture of Chlamydia Trachomatis were collected transcervically from the uterine cavity. The statistical analyses were calculated on the basis of Student t test. RESULTS: Immunological determinations showed the presence of antichlamydial antibodies in 43.6%. The endometrial cultures yielded growth of CT (36.6%) and histological signs of chlamydial endometritis were also discovered. This study pointed to the positive correlation between the results of endometrial biopsies (cultures), immunological (serological) investigations and clinical examinations showing that the chlamydial infection reached the Fallopian tubes from the endometrium which could result in infertility.
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