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  • Title: Investigating investment in biopharmaceutical R&D.
    Author: Carter PH, Berndt ER, DiMasi JA, Trusheim M.
    Journal: Nat Rev Drug Discov; 2016 Oct; 15(10):673-4. PubMed ID: 27616295.
    Abstract:
    Recent studies have highlighted a reduction in projected financial returns associated with biopharmaceutical R&D, owing to decreased productivity, increases in costs and flattening revenue per new drug, prompting calls for dramatic revisions to R&D models. On the basis of previous financial modelling, the simplest hypothesis would be that new investment in such R&D should be minimal and focused on biologics in preference to small molecules, as the internal rate of return on investment for biologics projects has been reported to be higher.
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