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  • Title: Enzymes of oxidant defence system of leucocytes and erythrocytes in bovine anaplasmosis.
    Author: More T, Reddy GR, Sharma SP, Singh LN.
    Journal: Vet Parasitol; 1989 Jun; 31(3-4):333-7. PubMed ID: 2763451.
    Abstract:
    The glutathione oxidant defence system in leucocytes and erythrocytes of six Anaplasma marginale-infected calves was examined by assaying glutathione peroxidase (GSH-px), glutathione reductase (GSSG-R), reduced glutathione (GSH) and superoxide dismutase (SOD). In addition, GSH-S-transferase and arginase levels were measured in leucocytes. There was a significant decline in the activities of leucocyte GSH-px, GSSG-R and SOD in the post-patent period; whereas arginase activity rose significantly following the patent period of anaplasmosis. The activity of erythrocyte SOD declined in the post-patent stage. The infection also caused a decline in red cell GSH (P less than 0.05). The results suggest that the glutathione oxidant defence system of peripheral blood cells is significantly influenced by the Anaplasma infection.
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