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  • Title: Arginine methyltransferase activity in chronic erythremic myelosis (Diguglielmo syndrome).
    Author: Kass L, Munster D.
    Journal: Biochim Biophys Acta; 1978 Jun 09; 524(2):497-500. PubMed ID: 276380.
    Abstract:
    Activity of S-adenosylmethionine-dependent arginine methyltransferase was substantially higher in sonicated bone marrow samples from 6 patients with chronic erythremic myelosis than in bone marrow from 3 patients with untreated pernicious anemia, 2 patients with autoimmune hemolytic anemia, and 4 normal persons. Increased activity of this enzyme may be one of the factors contributing to the pathogenesis fo methylated arginines in histones of erythroblasts from patients with chronic erythremic myelosis.
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