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Title: [Efficacy of reconstruction with modular endoprosthesis after resection of periacetabular malignant tumors].
Author: Guo X, Liu T, Li X, Li Z, Peng D, Zhang X, Zhang Q.
Journal: Zhong Nan Da Xue Xue Bao Yi Xue Ban; 2016 Sep 28; 41(9):962-8. PubMed ID: 27640795.
Abstract:
OBJECTIVE: To explore the efficacy of the resection of periacetabular malignant tumors and the reconstruction with modular endoprosthesis.  METHODS: From August 2006 to December 2012, 22 patients with periacetabular malignant tumors, who received the resection and reconstruction with modular prosthesis, were retrospectively reviewed. There were 11 males and 11 females, and the average age was 44 (16-65) years old. Pathological results showed there were 13 cases of chondrosarcoma, 5 cases of osteosarcoma, 2 cases of Ewing's sarcoma, 1 case of maligant fibrous histiocytoma, and 1 case of giant cell tumor. According to the classification system by Enneking, there were 11 cases of Type II+III resection, 5 cases of Type I+II+III resection, 3 cases of Type I+II resection, and 3 cases of Type II resection.  RESULTS: All patients were followed up. The average time for follow-up was 49 (11-103) months. At the last time of follow-up, 13 patients (59%) were still alive, 9 patients (41%) died due to their primary disease. Metastasis occurred in 8 patients (36%), and local recurrence occurred in 5 patients (23%). The mean Musculoskeletal Tumor Society (MSTS) score for 13 cases of alive patients at the latest time of follow-up was (18.5±5.7) months. The mean score for 11 patients, whose limb salvage were successful, was 20.7±2.0.  CONCLUSION: Reconstruction with modular prosthesis after wide resection for periacetabular malignant tumor can achieve satisfied outcome. 目的：探讨肿瘤切除后组配式假体重建治疗髋臼周围恶性骨肿瘤的疗效。方法：回顾性分析2006年8月至2012年12月接受肿瘤切除组配式半骨盆假体重建术治疗的髋臼周围恶性肿瘤患者22例，男性11例，女性11例，患者年龄44(16~65)岁。22例患者中软骨肉瘤13例，骨肉瘤5例，尤文氏肉瘤2例，恶性纤维组织细胞瘤1例，骨巨细胞瘤1例。按照Enneking骨盆肿瘤分区，II+III区为11例，I+II+III区为5例，I+II区为3例，II区为3例。结果：患者均获随访，随访时间为49(11~103)个月。至最后1次随访，无瘤存活13例(59%)，死亡9例(41%)。8例(36%)患者发生远处转移，5例(23%)患者发生局部复发。根据美国骨与软组织肿瘤协会评分标准，13例存活患者的评分为(18.5±5.7)分，其中11例患者保肢成功，其评分为(20.7±2.0)分。结论：髋臼周围恶性骨肿瘤扩大切除后组配式假体重建可获得较好的 疗效。.

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