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  • Title: Phenotypic expression of Hashimoto's thyroiditis is absolutely atypical in girls with Turner syndrome.
    Author: Salzano G, Calafiore M, Mignosa C, Passanisi S, Trombatore J, Zirilli G.
    Journal: Acta Biomed; 2016 Sep 13; 87(2):136-40. PubMed ID: 27648994.
    Abstract:
    BACKGROUND: It is unknown whether phenotypic expression of Hashimoto's thyroiditis (HT) might be conditioned by the association with Turner syndrome (TS). OBJECTIVES: To focus on the most recent pediatric studies concerning epidemiology and biochemical course of HT in TS girls. DESIGN: The epidemiological peculiarities of TS-related HT in pediatric age were compared with those usually observed in non-TS girls with HT and results are summarized in Tables 1 and 2. CONCLUSIONS: 1) phenotypical expression of HT in TS girls is significantly different from that observed in girls without TS; 2) such differences concern the epidemiological picture, the biochemical presentation modes and also the natural history from HT diagnosis onwards; 3) these peculiarities of TS-related HT are not necessarily linked with a specific karyotype.
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