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  • Title: Regurgitation across an obviously normal valve orifice as a possible prerequisite for non-organic cardiac murmur.
    Author: Stárek A, Niederle P, Spacek R, Suchan V, Feureisl R, Hes I, Kozák P, Hausnerová E.
    Journal: Cor Vasa; 1989; 31(3):186-94. PubMed ID: 2766751.
    Abstract:
    Using pulsed and continuous wave Doppler echocardiography, the author examined 359 subjects referred to ultrasound examination for a variety of reasons. Thorough examination of persons with morphologically unchanged valves revealed regurgitation in the tricuspid, pulmonary, mitral and aortic valves in 49.4%, 20%, 14.5% and 0.8%, respectively. The degree of regurgitation was invariably haemodynamically insignificant. Some patients had a positive finding in several valves at a time. Overall, regurgitation was found in 247 subjects (69%). While it is evident from the study that the finding of regurgitation in normal valves is relatively frequent, evaluation of its clinical importance remains an open question.
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