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  • Title: A model for testing antiseptic efficacy: a preliminary study on Betadine and Germidine.
    Author: Thamlikitkul V, Trakulsomboon S.
    Journal: J Med Assoc Thai; 1989 Jul; 72 Suppl 2():29-32. PubMed ID: 2769129.
    Abstract:
    Efficacy of povidone iodine antiseptic, betadine and germidine, was tested against normal skin flora and four pathogenic bacteria namely S. aureus, S. epidermidis, E. coli and Pseudomonas aeruginosa by a new model. The study was performed on the volar surface of forearms of ten patients. First of all, the skin flora was cultured then 10(8) cu/ml of the tested organisms was applied by a cotton swab and left to dry for 1 minute before the culture was repeated. Betadine or germidine was applied over the area previously painted with the organism. The culture was taken 1 to 2 minutes thereafter. The results showed that this model was feasible and convenient. Betadine and germidine are efficacious against normal skin flora and pathogenic bacteria.
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