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  • Title: Cerebral Erdheim-Chester disease: persistent enhancement with Gd-DTPA on MR images.
    Author: Tien RD, Brasch RC, Jackson DE, Dillon WP.
    Journal: Radiology; 1989 Sep; 172(3):791-2. PubMed ID: 2772189.
    Abstract:
    A case of Erdheim-Chester disease with intracerebral masses containing characteristic lipid-laden histiocytes is presented. These unusual lesions remained enhanced on magnetic resonance images obtained 8 days after injection of gadolinium diethylenetriaminepentaacetic acid (DTPA) dimeglumine. Chemical analysis of a biopsy specimen revealed a high concentration of gadolinium. Findings suggest that the Gd-DTPA complex or possibly a gadolinium-containing metabolite may be retained for extended periods in this unusual type of histiocytic lesion.
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