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  • Title: Acute coronary artery thrombosis in paroxysmal nocturnal hemoglobinuria.
    Author: Klein KL, Hartmann RC.
    Journal: South Med J; 1989 Sep; 82(9):1169-71. PubMed ID: 2772688.
    Abstract:
    We have reported a case of coronary artery thrombosis in a 36-year-old man with paroxysmal nocturnal hemoglobinuria (PNH), a potentially lethal thrombotic complication not previously documented in this unique patient population. Although the etiology of PNH remains unknown, the pathogenesis appears to be related to the deficiency of a specific membrane complement-regulatory protein, decay accelerating factor. Coronary artery thrombosis must now be added to the list of potential life-threatening thrombotic complications.
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