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  • Title: Relation between lymphocyte to monocyte ratio and short-term mortality in patients with acute pulmonary embolism.
    Author: Ertem AG, Yayla C, Acar B, Kirbas O, Unal S, Uzel Sener M, Akboga MK, Efe TH, Sivri S, Sen F, Gokaslan S, Topaloglu S.
    Journal: Clin Respir J; 2018 Feb; 12(2):580-586. PubMed ID: 27727508.
    Abstract:
    INTRODUCTION: The relationship between inflammation and mortality after acute pulmonary embolism (APE) has previously been investigated with different variables (platelet/lymphocyte ratio, etc). OBJECTIVES: We investigated the predictive value of lymphocyte to monocyte ratio (LMR) for mortality in first 30 days after APE. METHODS: The study population included 264 APE patients of which 230 patients were survivors, 34 patients were non-survivors. RESULTS: LMR was significantly lower in non-survivors after APE (P < .001). Neutrophil-to-lymphocyte ratio (NLR) was higher in non-survivors after APE (P < .001). Platelet-to-lymphocyte (PLR) had no significance between both groups (P: .241). Simplified pulmonary embolism severity index and LMR were independent predictors of mortality in patients with APE (P: .008 and P: .001, respectively). CONCLUSION: LMR as a novel marker of inflammation seemed to be an independent predictor of short-term mortality in patients with APE.
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