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  • Title: [Induction of an erection using papaverine].
    Author: Terek A, Sekei J, Getz F.
    Journal: Urol Nefrol (Mosk); 1989; (3):69-71. PubMed ID: 2773185.
    Abstract:
    In 61 patients erectile impotency was treated with papaverine injections into penile spongy body: initially 20-30 mg/day, then followed several days of intermittence, and then the dosages were built up with regard to the optimum time of erection for each person. Dosages higher than 80-100 mg were not advisable because of the evidence of prolonged erections. Recorded in 6 patients (7 times) prolonged erections lasted from 5 to 16 hrs (in 5 cases it was stopped by intracavernous injection of dopamine but in 2 patients cavernotomy was performed). A total of 300 sessions of papaverine intracavernous injections were made in 61 patients before the copulation (out of them 16 patients injected the drug themselves). During the treatment the patients were warned against prolonged erections: when it lasted for more than 4 hrs emergency clinical treatment be required for priapism prevention. It was proved that an adequate dosage of papaverine autoinjections into a spongy body was a simple, safe and effective method to cure erectile impotency, especially in patients with nonadvanced psychoneurological or vasculogenic disorders.
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