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  • Title: [Clinico-biochemical parallels in patients with early forms of syphilis and pathology of the cerebrospinal fluid].
    Author: Platonov SI, Burdak VN, Fedotov VP, Pogorelov VV.
    Journal: Vestn Dermatol Venerol; 1989; (5):58-62. PubMed ID: 2773584.
    Abstract:
    Altogether 160 patients with early syphilis have been examined (49 ones with primary seropositive, 36 with secondary new, 75 with secondary relapsing condition). Abnormalities in the cerebrospinal fluid have been detected in 49 (30.6%) patients, of these Stage I-II abnormalities in 9, Stage II-III in 26, and Stage III-IV in 14 cases. Clinically the patients with abnormal liquor have developed multiple erosive and ulcerous chancres, papular eruptions on the palms and soles, copious papular rash, wide condylomas, alopecia, leukoderma; analyses have revealed marked dysproteinemia, impaired protein production, absorption-excretory and enzymic functions of the liver. The changes have been the most severe in the patients with the liquor abnormalities who abused alcohol.
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