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  • Title: Cimetidine in the treatment of refractory anaphylaxis.
    Author: Yarbrough JA, Moffitt JE, Brown DA, Stafford CT.
    Journal: Ann Allergy; 1989 Sep; 63(3):235-8. PubMed ID: 2774306.
    Abstract:
    After preoperative intubation and administration of intravenous cefuroxime, a 48-year-old white female developed anaphylactic shock that was refractory to the usual therapeutic measures but was responsive to treatment with intravenous cimetidine. Beta-lactam sensitivity was subsequently confirmed by skin testing. Cimetidine, which antagonizes arterial H2 receptors, may be useful in the treatment of anaphylaxis refractory to the usual resuscitative measures.
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