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  • Title: Thalidomide in Refractory Tuberculomas and Pseudoabscesses.
    Author: Viel-Thériault I, Thibeault R, Boucher FD, Drolet JP.
    Journal: Pediatr Infect Dis J; 2016 Nov; 35(11):1262-1264. PubMed ID: 27753773.
    Abstract:
    Paradoxical immune reconstitution inflammatory syndrome is a well-described entity even in immunocompetent children, principally in association with Mycobacterium tuberculosis infections. Central nervous system involvement is a potential life-threatening form, sometimes refractory to standard treatment. We report the case of an HIV-negative refugee teenager, who presented with brain tuberculomas and pseudoabscesses responsive only to thalidomide.
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