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Pubmed for Handhelds

PUBMED FOR HANDHELDS

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  • Title: Handheld optical-resolution photoacoustic microscopy.
    Author: Lin L, Zhang P, Xu S, Shi J, Li L, Yao J, Wang L, Zou J, Wang LV.
    Journal: J Biomed Opt; 2017 Apr 01; 22(4):41002. PubMed ID: 27775746.
    Abstract:
    Optical-resolution photoacoustic microscopy (OR-PAM) offers label-free <italic<in vivo</italic< imaging with high spatial resolution by acoustically detecting optical absorption contrasts via the photoacoustic effect. We developed a compact handheld OR-PAM probe for fast photoacoustic imaging. Different from benchtop microscopes, the handheld probe provides flexibility in imaging various anatomical sites. Resembling a cup in size, the probe uses a two-axis water-immersible microelectromechanical system mirror to scan both the illuminating optical beam and resultant acoustic beam. The system performance was tested in vivo by imaging the capillary bed in a mouse ear and both the capillary bed and a mole on a human volunteer.
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