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  • Title: Pseudallescheria boydii keratomycosis in a horse.
    Author: Friedman DS, Schoster JV, Pickett JP, Dubielzig RR, Czuprynski C, Knoll JS, Wolfgram LJ.
    Journal: J Am Vet Med Assoc; 1989 Sep 01; 195(5):616-8. PubMed ID: 2777709.
    Abstract:
    The fungal organism Pseudallescheria boydii was isolated from the cornea of a Quarter Horse with ulcerative keratitis. Despite aggressive hourly medication through a subpalpebral lavage system, with drugs including miconazole and natamycin, the cornea developed a stromal abscess. Orbital exenteration was performed after 3 weeks. The fungal isolate was later determined to be resistant to all 8 antifungal drugs tested. Microscopic examination of the cornea revealed fungal hyphae throughout the corneal stroma and penetrating the Descemet membrane. Pseudallescheria boydii has not been implicated previously as a cause of keratomycosis in horses or in other domestic animals, although cases in human beings have been described.
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