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  • Title: Impact of MDT on incidence rates of leprosy among household contacts. Part 1. Baseline data.
    Author: Sundar Rao PS, Jesudasan K, Mani K, Christian M.
    Journal: Int J Lepr Other Mycobact Dis; 1989 Sep; 57(3):647-51. PubMed ID: 2778370.
    Abstract:
    This preliminary study from Gudiyatham Taluk, the leprosy control area of the Schieffelin Leprosy Research & Training Centre, investigated the incidence rates of leprosy among household contacts during the period 1970-1985. The incidence rates of leprosy among the household contacts prior to and during the initiation of multi-drug therapy are presented here. The overall incidence rate among the household contacts was 4 per 1000 person-years at risk. Contacts of multibacillary and paucibacillary cases had a relative risk of 3-6 times and 2-4 times the risk of leprosy in the general population, respectively. The incidence rates among children were higher than adults; the peak age-specific incidence rate was between 5-9 years, and nearly one third of the primary cases were children. These findings are presented and the methodological issues discussed.
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