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  • Title: Sodium Nitrite Inhibits Killing of Pseudomonas aeruginosa Biofilms by Ciprofloxacin.
    Author: Zemke AC, Kocak BR, Bomberger JM.
    Journal: Antimicrob Agents Chemother; 2017 Jan; 61(1):. PubMed ID: 27799207.
    Abstract:
    Sodium nitrite inhibits bacterial respiration and is in development as an antimicrobial for chronic bacterial infections associated with cystic fibrosis. The goal of the current study was to investigate the interaction between nitrite and ciprofloxacin. Using liquid culture killing assays and a biotic biofilm model, we observed that nitrite induces tolerance of ciprofloxacin.
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