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  • Title: In-vivo retinal imaging with off-axis full-field time-domain optical coherence tomography.
    Author: Sudkamp H, Koch P, Spahr H, Hillmann D, Franke G, Münst M, Reinholz F, Birngruber R, Hüttmann G.
    Journal: Opt Lett; 2016 Nov 01; 41(21):4987-4990. PubMed ID: 27805666.
    Abstract:
    With a simple setup, mainly composed of a low coherence light source and a camera, full-field optical coherence tomography (FF-OCT) allows volumetric tissue imaging. However, fringe washout constrains its use in retinal imaging. Here, we present a novel motion-insensitive approach to FF-OCT, which introduces path-length differences between the reference and the sample light in neighboring pixels using an off-axis reference beam. The temporal carrier frequency in scanned time-domain OCT is replaced by a spatial carrier frequency. Volumetric in-vivo FF-OCT measurements of the human retina were acquired in only 1.3 s, comparable to the acquisition times of current clinically used OCT devices.
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