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  • Title: [The formation and repair of DNA breaks in subpopulations of irradiated rat bone marrow cells].
    Author: Tronov VA, Provotorov AV, Kaz'min GIu, Danilian VG, Rad'ko SP.
    Journal: Radiobiologiia; 1989; 29(4):451-6. PubMed ID: 2780977.
    Abstract:
    Using the method of viscosimetry of alkaline lysates it was shown that the saturable DNA repair system was present in rat bone marrow cells which was described by a complex kinetics. Isokinetic fractionation in a sucrose and dextran gradient permitted to isolate three fractions differing in the ratio between differentiated cells and cells capable of division. The estimation of the postirradiation DNA repair kinetics in these cells revealed a comparatively high level of repair in normocytes which confirmed the presence of the relationship between the level of DNA repair in cells and their proliferative potency.
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