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  • Title: [Treatment efficacy in destructive forms of pulmonary tuberculosis in relation to the methods of administering rifadin and isoniazid].
    Author: Shevchenko RN, German AK, Akhtyrskiĭ AI, Smirnova VV.
    Journal: Vrach Delo; 1989 Jun; (6):76-8. PubMed ID: 2781771.
    Abstract:
    The efficacy was studied of 130 patients with freshly detected destructive forms of pulmonary tuberculosis depending on the method of administration of rifadin and isoniazid. Treatment of pulmonary tuberculosis was realized with rifadin, isoniazid and streptomycin. Three groups of patients were distinguished. In group I rifadin and isoniazide was taken orally, in group II--rifadin was administered orally and intrabronchially, isoniazid--orally. In group III rifadin was orally and intrabronchially, isoniazid--intravenously. The treatment was more effective with combined administration of rifadin and intravenous administration of isoniazid.
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