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  • Title: Molecularly imprinted polymers for bioanalytical sample preparation.
    Author: Gama MR, Bottoli CB.
    Journal: J Chromatogr B Analyt Technol Biomed Life Sci; 2017 Feb 01; 1043():107-121. PubMed ID: 27825628.
    Abstract:
    Molecularly imprinted polymers (MIP) are stable polymers with molecular recognition abilities, provided by the presence of a template during their synthesis, and are excellent materials with high selectivity for sample preparation in bioanalytical methods. This short review discusses aspects of MIP preparation and its applications as a sorbent material in pharmaceutical and biomedical analysis. MIP in different extraction configurations, including classical solid-phase extraction, solid-phase microextraction, magnetic molecularly imprinted solid-phase extraction, microextraction by packed sorbent and solid-phase extraction in pipette tips, are used to illustrate the good performance of this type of sorbent for sample preparation procedures of complex matrices, especially prior to bioanalytical approaches.
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