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  • Title: [Panel of monoclonal antibodies to CD38 antigen].
    Author: Baryshnikov AIu, Dubinkin IV, Korotkova OV, Tupitsyn NN, Shvartsbergs AM.
    Journal: Biull Eksp Biol Med; 1989 Jan; 107(1):74-7. PubMed ID: 2783655.
    Abstract:
    The panel of monoclonal antibodies (MCA) ICO-16, ICO-17, ICO-18, ICO-19, ICO-20, ICO-27, ICO-28 IgG2a isotypes to CD38 antigen was obtained. MCA discovered the antigen with 45 kD molecular mass, expressed on the surface of 100% thymocytes, 43-53% lymphocytes, 32-46% monocytes. All obtained MCA blocked the binding each other with thymocyte of man. MCA reacts in complement-dependent cytotoxic test. The antigen CD38 is expressed on blast cells of patients with T-cells subset of ALL.
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