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  • Title: Taurolidine in Pediatric Home Parenteral Nutrition Patients.
    Author: Hulshof EC, Hanff LM, Olieman J, de Vette S, Driessen GJ, Meeussen C, Escher JC.
    Journal: Pediatr Infect Dis J; 2017 Feb; 36(2):233-235. PubMed ID: 27846059.
    Abstract:
    To reduce the incidence of catheter-related bloodstream infections in home parenteral nutrition patients, the use of taurolidine was introduced in the Sophia Children's Hospital in 2011. This introduction led to a reduction in catheter-related bloodstream infections: 12.7/1000 catheter days before the use of taurolidine, compared with 4.3/1000 catheter days afterwards (n = 7) [relative risk = 0.36, 95% confidence interval: 0.20-0.65 (P = 0.018)].
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