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  • Title: Cis-platin-Mecy as salvage chemotherapy in recurrent advanced ovarian carcinoma.
    Author: Belli M, Colantuoni G, Di Iorio B.
    Journal: G Ital Oncol; 1989; 9(1):31-3. PubMed ID: 2785083.
    Abstract:
    Cis-platin (DDP) has proved to be highly active in the treatment of ovarian adenocarcinoma. The Authors have treated 12 patients with istologically proven advanced ovarian carcinoma with a type of alternating regimen consisting of four weekly DDP courses (1 mg/kg b.w./week) followed by monthly courses high-dose methotrexate (750 mg/mq i.v.) plus cyclophosphamide (250 mg/mq for 5 days) (Mecy). The alternating regimen DDP + Mecy proved to have significant activity as a salvace chemiotherapy regimen for patients with advanced ovarian carcinoma.
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