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  • Title: [Pre- and postpartum hemostasis in type II Willebrand-Jürgens syndrome].
    Author: Lutze G, Canzler E, Franke D, Töpfer G.
    Journal: Z Gesamte Inn Med; 1989 Feb 15; 44(4):117-20. PubMed ID: 2785733.
    Abstract:
    In a female patient with a von Willebrand's disease type II (ristocetin cofactor less than 20%) shortly before and after birth of a son the factor VIII-related antigen and the ristocetin cofactor showed considerable increases, which some weeks later again decreased to the original values. Despite additional thrombocytopenia only on the 4th day post partum an easily controllable uterine haemorrhage was to be established. The risk of haemorrhage in von Willebrand's disease during pregnancy, birth and puerperium seems to be insignificant; nevertheless on the basis of the heterogeneity of this disease a peripartal coagulation-analytic control is regarded necessary.
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