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Title: Lethal distemper in badgers (Meles meles) following epidemic in dogs and wolves. Author: Di Sabatino D, Di Francesco G, Zaccaria G, Malatesta D, Brugnola L, Marcacci M, Portanti O, De Massis F, Savini G, Teodori L, Ruggieri E, Mangone I, Badagliacca P, Lorusso A. Journal: Infect Genet Evol; 2016 Dec; 46():130-137. PubMed ID: 27876612. Abstract: Canine distemper virus (CDV) represents an important conservation threat to many wild carnivores. A large distemper epidemic sustained by an Arctic-lineage strain occurred in Italy in 2013, mainly in the Abruzzi region, causing overt disease in domestic and shepherd dogs, Apennine wolves (Canis lupus) and other wild carnivores. Two badgers were collected by the end of September 2015 in a rural area of the Abruzzi region and were demonstrated to be CDV-positive by real time RT-PCR and IHC in several tissues. The genome of CDV isolates from badgers showed Y549H substitution in the mature H protein. By employing all publicly available Arctic-lineage H protein encoding gene sequences, six amino acid changes in recent Italian strains with respect to Italian strains of dogs from 2000 to 2008, were observed. A CDV strain belonging to the European-wildlife lineage was also identified in a fox found dead in the same region in 2016, proving co-circulation of an additional CDV lineage.[Abstract] [Full Text] [Related] [New Search]