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Title: Three new drimane sesquiterpenoids from cultures of the fungus Penicillium sp. Author: Ding JH, Ding ZG, Chunyu WX, Zhao JY, Wang HB, Liu SW, Wang F. Journal: J Asian Nat Prod Res; 2017 Aug; 19(8):780-785. PubMed ID: 27892687. Abstract: Three new drimane sesquiterpenoids, 12-hydroxyalbrassitriol (1), drim-8(12)-en-6β,7α, 9α,11-tetraol (2), and drim-68(12)-dien-9α,11-diol (3), along with one known analog albrassitriol (4), were isolated from cultures of the tin mine tailings-associated fungus Penicillium sp. The new structures were determined on the basis of extensive spectroscopic analyses. All compounds were tested for their cytotoxicities against five human cancer cell lines.[Abstract] [Full Text] [Related] [New Search]