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  • Title: [Surfactant surface activity and ultrastructural changes in the type-II alveolocytes of fetal and neonatal lungs in experimental inflammation of the maternal lungs].
    Author: Zagorul'ko AK, Fat LF, Safronova LG, Kobozev GV, Gorelik NI.
    Journal: Biull Eksp Biol Med; 1989 Jun; 107(6):753-6. PubMed ID: 2790177.
    Abstract:
    The lungs of 19 guinea pigs, born from 8 females in which acute and chronic pneumonia had been modelled by transtracheal introduction of sterile fishing-line were investigated. It was established, that in guinea pigs, born in females with acute and chronic pneumonia, the functional immaturity of pneumocytes of the 2-nd type took place. The functional immaturity of pneumocytes of the 2-nd type results in suppression of the surface active characteristics of surfactant.
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