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  • Title: Pheochromocytoma in neurofibromatosis type 1 during pregnancy.
    Author: Remón-Ruiz P, Aliaga-Verdugo A, Guerrero-Vázquez R.
    Journal: Gynecol Endocrinol; 2017 Feb; 33(2):93-95. PubMed ID: 27908211.
    Abstract:
    Pregnant women with neurofibromatosis type 1 (NF-1) have increased complications during gestation, including hypertensive disorders that are sometimes caused by pheochromocytoma. Pheochromocytoma is an extremely rare condition during pregnancy, and the main clinical manifestation is hypertension. If not properly treated, pheochromocytoma has high maternal and fetal mortality rates. Early recognition and adequate clinical management before delivery have led to better outcomes in the last few decades. Despite the association of NF-1 and pheochromocytoma, there are few clinical reports of these two conditions in pregnant patients. We present a rare case of pheochromocytoma diagnosed during pregnancy in a patient with NF-1, and we describe the treatment and the obstetric and fetal outcomes. We also review other medical conditions related to NF-1 that complicated this patient's pregnancy.
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