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  • Title: Attempts at clarification of splenic visualization on reticuloendothelial images: Tc-99m DISIDA compared with heat- denatured Tc-99m RBC imaging.
    Author: Dunn EK, Vaquer RA, Strashun AM.
    Journal: Clin Nucl Med; 1989 Sep; 14(9):647-50. PubMed ID: 2791418.
    Abstract:
    Four patients with enlarged left hepatic lobes and questionable or difficult splenic visualization on Tc-99m sulphur colloid (SC) images were further examined with additional radionuclide procedures. All four patients had Tc-99m DISIDA imaging, and three of them also had heat-denatured Tc-99m RBC imaging. The hepatobiliary images appear very effective in confirming postsplenectomy expanded enlargement of the left lobe of the liver and in refuting the presence of spleen in such cases. However, distinct visualization of the spleen in these patients can be achieved only through selective spleen imaging with heat-damaged red cells.
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