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  • Title: [Effect of splenic humoral factors on the cholinesterase activity of liver tissue and blood serum in experimental toxic hepatitis in rats].
    Author: Shevchenko AV, Korpachev VV, Tychinin VA.
    Journal: Fiziol Zh (1978); 1989; 35(4):24-7. PubMed ID: 2792437.
    Abstract:
    Activity of cholinesterase in the liver of rats with experimental toxic hepatitis decreases, while in the serum it remains unchanged. Introduction of splenin, a spleen preparation, normalizes indices of the cholinesterase activity, extract of muscles possessing no such property. Boiling-heated spleen preparation looses its activity. Activity of the studied enzyme remains unchanged both after splenectomy and splenin introduction to intact animals.
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