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  • Title: [Patterns of the forming of an immunologic memory to staphylococcal corpuscular antigen].
    Author: Liashchenko KP, Bobrovnik SA, Golovanova TA.
    Journal: Fiziol Zh (1978); 1989; 35(4):27-32. PubMed ID: 2792438.
    Abstract:
    The experiments carried out on inbred mice have revealed that the level of the immunological memory to staphylococci depends on the intensity of the antigenic stimulation; high priming dose of antigen proving to be the most effective one. The opposite character of immune responsiveness observed during primary antibody response to particulate staphylococcal antigen in C3H and A/Sn mice increased after the second immunization. It is established that immunological memory to staphylococci may be induced in genetically athymic mice. Many antibody-forming cells are found in the bone marrow of the secondary immunized mice. This phenomenon may be due to the repopulation of the bone marrow tissue by recirculating memory cells.
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