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  • Title: Adverse reactions to iopamidol and iohexol myelography with special attention to headache: role of myelographic technique.
    Author: Sobel DF, Rowe R, Zyroff J, Koziol JA, Frost F, Krupsaw J.
    Journal: Headache; 1989 Sep; 29(8):519-22. PubMed ID: 2793457.
    Abstract:
    In order to identify those myelographic risk factors associated with a higher incidence of adverse effects, myelographic technique, patient variables and post-myelographic symptoms were prospectively recorded in a group of 152 patients studied with iopamidol and in a second group of 28 patients studied with iohexol. None of the technical factors studied were identified to have a statistically significant relationship with the incidence of adverse reactions. Older patients fared better than younger patients in both groups. Overall, there was a lower incidence of side effects in the iopamidol group (29%) than in the iohexol group (50%). Headache, nausea, and vomiting were the most frequent reactions seen.
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