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  • Title: [Current status of treatment of refractory ascites in patients with liver cirrhosis].
    Author: Shao J, Zhang L, Han GH, Fan DM.
    Journal: Zhonghua Gan Zang Bing Za Zhi; 2016 Oct 20; 24(10):721-723. PubMed ID: 27938554.
    Abstract:
    Ascites is a common clinical manifestation of cirrhotic portal hypertension, and about 60%-80% of cirrhotic patients develop the symptom of ascites within 10 years. Once ascites occurs, the 5-year survival rate is reduced from 80% to 50%. With the progression of liver diseases, approximately 5%-10% of patients with ascites develop refractory ascites, and the median survival time is only 6-12 months. This article reviews the definition and diagnosis of refractory ascites, evaluation of prognostic factors, and treatment regimens, including large-volume paracentesis combined with protein supplementation, transjugular intrahepatic portosystemic shunt, and liver transplantation.
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