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  • Title: [Precancerous lesions of the buccal epithelium].
    Author: Renaud-Vilmer C, Cavelier-Balloy B.
    Journal: Ann Dermatol Venereol; 2017 Feb; 144(2):100-108. PubMed ID: 27939087.
    Abstract:
    Squamous cell carcinomas of the oral cavity and lips consistently have a high incidence (they constitute the fifth most common form of cancer in France) and carry a heavy prognosis, particularly if diagnosed late. According to different studies, between 10 and 80% of such carcinomas occur in a pre-existing or precancerous lesion. The World Health Organisation (WHO) recommends the use of two terms for such lesions: precursor lesions, i.e. histological lesions associated with intraepithelial neoplasia (IEN) and verrucous hyperplasia (VH), frequently resulting clinically in leukoplakia or erythroplakia; "at risk" lesions, which include lichen planus, submucosal oral fibrosis and certain forms of genodermatosis.
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