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  • Title: Alteration of lidocaine-induced convulsions by meperidine and nitrous oxide.
    Author: Gangarosa LP, Ciarlone AE, Hung C.
    Journal: J Dent Res; 1978; 57(5-6):752-4. PubMed ID: 279595.
    Abstract:
    When mice were pretreated with meperidine, the incidence of lidocaine-induced convulsions was increased. Nitrous oxide-oxygen (N2O-02) offered no protection against convulsions caused by lidocaine alone but lowered the incidence of lidocaine-induced convulsions of mice pretreated with meperidine.
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